Identification and characterisation of MCLA-158 as an anti-EGFRxLGR5 bispecific antibody that potently inhibits patient-derived CRC organoid growth

Rob C. Roovers, Bram Herpers, Mark James, Berina Eppink, Carme Cortina, David Maussang-Detaille, Ingrid Kolfschoten, Sylvia F. Boy, Marc van de Wetering, Wim de Lau, Robert Doornbos, Carina Clements, Abdul Basmeleh, Willem Bartelink, Vanessa Zondag van de Zande, Kuan Yan, Lucia Salinaro, Lex Bakker, John de Kruif, Hans Clevers, Robert Vries, Eduard Batlle, Leo Price, and Mark Throsby. Poster presented at the American Association for Cancer Research (AACR) 2017 Annual Meeting, Washington, DC, USA.