Generation of Wnt- and mitogenic receptor binding bispecific antibodies to target cancer stem cells

Berina Eppink1, Rob Roovers1, Bram Herpers2, Wim de Lau3, Carina Clements1, Vanessa Zondag van der Zande1, Abdul Basmeleh1, Willem Bartelink1, Marc van de Wetering3,4, Robert Vries3,4, Leo Price2, John de Kruif1, and Mark Throsby11Merus BV Utrecht, Netherlands; 2OcellO BV, Leiden, Netherlands; 3Hubrecht Institute, Utrecht, Netherlands; 4HUB, Utrecht, Netherlands.

Poster presented at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, Boston, MA, USA.